The largest off-shore island in Africa is the island of Madagascar. It is located off the east coast of Africa in the Indian Ocean and is the fourth largest island in the world. The island is home to a diverse range of plants and animals, many of which are found nowhere else in the world. Madagascar has a rich cultural heritage, with a mix of African, Asian and European influences. The island is known for its unique wildlife, stunning landscapes, and beautiful beaches, making it a popular tourist destination.