The expression Agwo gbagburu ochu is an Igbo proverb. Literally, it translates as "the snake has killed in pursuit" or "the snake has committed murder." In Igbo proverbial usage, the snake (agwo) symbolises danger and harm, and gbagburu ochu (killed/committed murder) signifies an irreversible harmful act.
This proverb is used when something bad has already happened and cannot be undone. It conveys that the damage is done - the harmful act has been committed, and there is no reversing it. The correct meaning is therefore Ihe ojoo emewo (a bad deed has been done).
The other options do not capture the proverb's meaning. A woman refusing marriage (nwanyi juru alu), a trickster (ezigbo onye aghuugho), or an unknown friend (onye enyi na-amaghi) are unrelated to the proverb's message about irreversible harm.