Inbreeding is highly discouraged in humans primarily because it can greatly increase the risk of hereditary diseases. When close relatives, who may share similar genetic traits, have children together, there is a higher probability that both parents carry the same recessive genes. These recessive genes could cause genetic disorders if inherited in pairs. In an outbred population, these recessive genes are less likely to pair up, thereby reducing the risk of such disorders.
Hereditary diseases include conditions like cystic fibrosis, sickle cell anemia, and Tay-Sachs disease. These diseases can cause severe health problems and affect the quality of life of those born with them. The higher genetic similarity between parents who are closely related increases the chances of these diseases manifesting in their offspring.
In addition, inbreeding can also lead to the phenomenon known as "inbreeding depression," which can cause a reduction in fertility, survivability, and growth rates due to the accumulation of deleterious alleles. This can contribute to an increased death rate of newborns or result in other developmental concerns.
In summary, inbreeding increases the likelihood of harmful genetic conditions being expressed and can significantly impact the health and survival of the offspring, which is why it is strongly discouraged in human societies.