CORE Biology (Short Course) - 9221 OxfordAQA

Genetic Manipulation

Overview

Somewhere in a laboratory, a single gene is lifted out of the chromosomes of one species and dropped into the cells of another. The organism that receives it goes on to grow a characteristic that nothing in its ancestry could ever have given it: a maize plant that poisons the caterpillars feeding on it, a crop that shrugs off a weedkiller which flattens everything green around it. Nothing about the plant is a copy of anything. One instruction has been added, and the rest of the organism is exactly as it was.

This lesson follows that single gene the whole way: out of one chromosome, into a carrier, through a cell wall and into a crop growing in a field. You will learn the three stages the specification asks you to name, why the timing of the transfer decides whether the characteristic shows up in one leaf or in all of them, what genetically modified crops are actually built to do, and why the arguments about them are still running. That last part carries marks of its own: OxfordAQA expects you to read information you have never seen before about genetic engineering and reach a judgement you can defend from it.

Objectives

  1. In genetic engineering, genes from the chromosomes of humans and other organisms can be ‘cut out’ and transferred to cells of other organisms: enzymes are used to isolate the required gene; this gene is inserted into a vector, usually a bacterial plasmid or a virus 38 ; the vector is used to insert the gene into the required cells.
  2. Genes can also be transferred to the cells of animals, plants or microorganisms at an early stage in their development so that they develop with desired characteristics.
  3. Crops that have had their genes modified in this way are called genetically modified (GM) crops. GM crops include ones that are resistant to insect attack or to herbicides.
  4. GM crops generally show increased yields.
  5. Concerns about GM crops include the effect on populations of wild flowers and insects, and uncertainty about the effects of eating GM crops on human health. Students should be able, when provided with appropriate information, to interpret information about genetic engineering techniques and to make informed judgements about issues concerning genetic engineering, including GM crops.

Mind map

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Lesson Note

A biotechnologist who wants a crop plant to defend itself against insects does not wait for the right plant to turn up. She goes and finds an organism that already has the characteristic, takes the gene responsible out of its chromosomes, and puts that gene into the crop. The idea rests on one fact you already met in Cell Division: chromosomes carry genes, and those genes control the characteristics of the body. If a characteristic is controlled by a gene, and a gene is a length of chemical that can be cut and moved, then a characteristic can be moved too.

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Lesson Evaluation

Congratulations on completing the lesson on Genetic Manipulation. Now that youve explored the key concepts and ideas, its time to put your knowledge to the test. This section offers a variety of practice questions designed to reinforce your understanding and help you gauge your grasp of the material.

You will encounter a mix of question types, including multiple-choice questions, short answer questions, and essay questions. Each question is thoughtfully crafted to assess different aspects of your knowledge and critical thinking skills.

Use this evaluation section as an opportunity to reinforce your understanding of the topic and to identify any areas where you may need additional study. Don't be discouraged by any challenges you encounter; instead, view them as opportunities for growth and improvement.

  1. In genetic engineering, what is usually used as a vector? A. A ribosome B. A red blood cell C. A bacterial plasmid D. A chromosome pair Answer: C
  2. What is used to isolate the required gene from a chromosome in genetic engineering? A. Enzymes B. A herbicide C. An electric shock D. A mineral ion solution Answer: A
  3. Which of these is a plasmid? A. A small circle of DNA in the cytoplasm of a bacterium B. A structure that joins two chromosomes together C. A gamete produced by a flowering plant D. A substance that kills insect larvae Answer: A
  4. A GM crop is described as herbicide resistant. What does this allow the farmer to do? A. Harvest the crop before it is ripe B. Spray the field so that the weeds die but the crop survives C. Grow the crop without any mineral ions in the soil D. Produce identical copies of the crop plant Answer: B
  5. Which of these is a concern raised about growing GM crops? A. GM crops generally give lower yields B. GM crops cannot be resistant to herbicides C. GM crops may affect populations of wild flowers and insects D. GM crops contain no genes of their own Answer: C

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