The disadvantage of complexity of organisation in the higher organisms is that it leads to

The disadvantage of complexity of organisation in the higher organisms is that it leads to a slower rate of diffusion of oxygen to individual cells. In higher organisms, such as animals and plants, there is an intricate network of tissues and organs that work together to perform vital functions. This complexity requires a vast amount of energy to maintain and a greater reliance on oxygen for cellular respiration. However, as organisms get bigger and more complex, the distance between the surface of the organism and the innermost cells increases, resulting in a slower rate of diffusion of oxygen to individual cells. This can limit the size of organisms and their ability to survive in low-oxygen environments.