Which disease is sex-linked and mainly afflicts male offspring?

The disease that is sex-linked and mainly affects male offspring is called haemophilia. This is because the gene that causes haemophilia is located on the X chromosome. Since females have two X chromosomes, if they inherit one copy of the haemophilia gene, they usually have a healthy copy on their other X chromosome to compensate. However, males only have one X chromosome, so if they inherit the haemophilia gene from their mother, they will develop the disease. Females can also be carriers of the haemophilia gene and pass it on to their male offspring. Haemophilia is a bleeding disorder that affects the blood's ability to clot properly, leading to excessive bleeding and bruising.