There are 250 boys and 150 girls in a school, if 60% of the boys and 40% of the girls play football, what percentage of the school play football?

We are given that there are 250 boys and 150 girls in a school. We are also given that 60% of the boys play football, which means that 0.6 x 250 = 150 boys play football. Similarly, 40% of the girls play football, which means that 0.4 x 150 = 60 girls play football. Therefore, the total number of students who play football is 150 + 60 = 210. To find the percentage of the school that plays football, we need to divide the number of students who play football by the total number of students in the school and multiply by 100. The total number of students in the school is 250 + 150 = 400. So, the percentage of the school that plays football is (210/400) x 100 = 52.5%. Therefore, the correct option is 52.5% (option D).