(a) List four characteristics which can be genetically transmitted in humans.
(b)(i) Name two sites eac• in plants and animals where meiosis occurs.
(ii) State two differences between meiosis and mitosis
(c) A woman with blood group 'A' (heterozygous) claimed that her son who has blood group '0' was fathered by Mr. James who has blood group 'A' (homozygous). With the aid of suitable genetic diagrams
(i) prove or disprove the woman's claim
(ii) give reasons to support your answer.
(a) Four characteristics that can be genetically transmitted in humans
- Blood group (ABO / Rhesus).
- Skin (and eye) colour.
- Ability to roll the tongue.
- Height (and shape of the nose, hair type, colour blindness, sickle-cell trait).
(b)(i) Two sites each where meiosis occurs
In plants: the anther (in the pollen sacs) and the ovule (embryo sac) of the flower.
In animals: the testes (in males) and the ovaries (in females).
(b)(ii) Two differences between meiosis and mitosis
| Meiosis | Mitosis |
|---|
| Produces four daughter cells | Produces two daughter cells |
| Daughter cells have half the chromosome number of the parent (haploid) | Daughter cells have the same chromosome number as the parent (diploid) |
(c) Blood-group paternity test
The ABO blood groups are controlled by three alleles: IA and IB (co-dominant) and i (recessive). Group O is ii.
Genotypes given:
- Woman: blood group A, heterozygous = IAi
- Son: blood group O = ii
- Mr James: blood group A, homozygous = IAIA
For the son to be group O (ii), he must receive an i allele from each parent. The mother (IAi) can supply an i allele. The alleged father must therefore also supply an i allele.
Cross: mother IAi \( \times \) Mr James IAIA
| Gametes | IA | i |
|---|
| IA | IAIA (group A) | IAi (group A) |
| IA | IAIA (group A) | IAi (group A) |
(i) Conclusion: All possible children of this cross are blood group A (IAIA or IAi). None can be group O. Therefore the woman's claim is disproved: Mr James cannot be the father of the group O son.
(ii) Reason: Mr James, being homozygous group A (IAIA), can only pass on an IA allele. A group O child must receive an i allele from both parents, so a homozygous group A man cannot father a group O child.