His many years of success in legal practise.... didn't come out without challenges
Answer Details
The most appropriate option to complete the sentence is "didn't come out without challenges, however". This is because the phrase "didn't come out without challenges" indicates that the person faced difficulties in their legal practice. The word "however" is used to show a contrast or contradiction to what came before, in this case, the success that the person achieved. Therefore, the complete sentence would read, "His many years of success in legal practice didn't come out without challenges, however."