While humans and many other species have red blood, due to the iron in their hemoglobin, other animals have different colored blood. Spiders (as well as horseshoe crabs and certain other arthropods) have blue blood due to the presence of copper-based hemocyanin in their blood. Some animals, such as the sea cucumbers, even have yellow blood. What could make blood yellow? The yellow coloration is due to a high concentration of the yellow vanadium-based pigment, vanabin. Unlike hemoglobin and hemocyanin, vanabin does not seem to be involved in oxygen transport.