Inflation can be defined as the persistent increase in the general price level of goods and services over time. One major disadvantage of inflation is that it leads to a decrease in the purchasing power of money, which in turn affects fixed income earners negatively. When there is inflation, the cost of goods and services goes up, but the income of fixed income earners remains constant. This means that the amount of goods and services they can purchase with their income decreases. As a result, their real income reduces, and they are worse off. Therefore, the correct answer is fixed income earners lose.