Region pH mouth 7 stomach 2 duodenum 8 ileum 8 The conditions inside the alimentary canal are not the same all the way along it. Each region has its own pH,...

Assessment: Biology (9-1) 0970 | Paper 4 Mock 01 | Theory (Extended) Subject: Biology (9-1) - 0970

Question 1 Report

RegionpH
mouth7
stomach2
duodenum8
ileum8

The conditions inside the alimentary canal are not the same all the way along it. Each region has its own pH, which suits the enzymes that work there. A student used a pH probe to measure the pH of the contents of four different regions of the canal a short time after a person had eaten a meal. The results are shown in Table 9.1.

(a) State the region shown in the table that has the lowest pH. [1]
(b) Name an enzyme that works best in the conditions found in the stomach. [1]
(c) Explain how the low pH of the stomach both aids digestion and helps to protect the body. [3]
(d) Describe how the pH changes between the stomach and the duodenum, and explain how this change is brought about. [3]
(e) Name the alkaline secretion that helps to raise the pH in the duodenum. [1]
(f) Explain why enzymes that act in the duodenum would not work well at pH 2. [3]
(g) State the general term for the breakdown of large food molecules into small soluble ones. [1]

Answer Details

This question tests how pH varies along the alimentary canal and why each region suits its own enzymes. A pH probe reading shows that conditions change sharply from the acidic stomach to the alkaline duodenum.

(a) The region with the lowest pH is the stomach [1].

(b) An enzyme that works best in stomach conditions is pepsin [1].

(c) The low pH of the stomach both aids digestion and protects the body: the acid provides the optimum pH for pepsin, so protein digestion is fast [1]; it kills bacteria / pathogens in the food [1]; thereby protecting the body from infection [1].

(d) Between the stomach and duodenum the pH rises / becomes alkaline (from about 2 to 8) [1]; because alkaline bile and pancreatic juice enter the duodenum [1]; and these neutralise the acid from the stomach [1]. The change is a deliberate switch of conditions to suit intestinal enzymes.

(e) The alkaline secretion that raises the pH is bile / pancreatic juice [1].

(f) Duodenal enzymes would not work at pH 2 because their optimum pH is alkaline (about 8) [1]; at pH 2 the active site changes shape / the enzyme is denatured [1]; so substrate no longer fits and digestion stops [1].

(g) The breakdown of large food molecules into small soluble ones is called digestion [1].

Exam tip: connect each region's pH to the enzymes released there - acid for pepsin in the stomach, alkali for intestinal enzymes - and remember that neutralisation by bile and pancreatic juice is what drives the pH up.

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