The effect of chlorofluorocarbon is the depletion of the ozone layer. Chlorofluorocarbons (CFCs) are chemicals that were once commonly used in refrigeration, air conditioning, and aerosol sprays. When they are released into the atmosphere, they rise up to the ozone layer and break down the ozone molecules, leading to a reduction in the thickness of the ozone layer. This can have serious consequences, as the ozone layer helps protect the Earth from harmful ultraviolet radiation from the sun. Without the ozone layer, more UV rays can reach the Earth's surface, leading to increased risks of skin cancer, cataracts, and other health problems, as well as negative effects on plant and animal life.