Which of the following is a measure of the average kinetic energy of the molecules of a substance?

The measure of the average kinetic energy of the molecules of a substance is called temperature. Temperature is a measure of how hot or cold a substance is and is directly related to the kinetic energy of the particles in that substance. The higher the temperature, the more kinetic energy the particles have, and the faster they move. Conversely, the lower the temperature, the less kinetic energy the particles have, and the slower they move. Therefore, temperature is the correct option that measures the average kinetic energy of the molecules of a substance. Volume, mass, and pressure are not related to the average kinetic energy of the molecules of a substance.