Biology - 4BI1 PearsonEdexcel

Cloning

Gbogbo ọrọ náà

In 1996 a single sheep made headlines around the world. Dolly was the first mammal cloned from an adult body cell, proving that a fully differentiated cell still contains all the genetic information needed to build an entire organism. Cloning - producing genetically identical copies - is not just a laboratory curiosity: it underpins a huge plant propagation industry and opens the door to producing human proteins from animal milk.

This topic covers plant cloning through micropropagation (tissue culture), the stages of adult cell cloning as illustrated by Dolly, and the use of cloned transgenic animals to manufacture valuable human proteins. You will explore the advantages, limitations, and ethical questions surrounding each technique.

Ebumnobi

Describe the process of micropropagation (tissue culture) in which explants are grown in vitro
Understand how micropropagation can be used to produce commercial quantities of genetically identical plants with desirable characteristics
Describe the stages in the production of cloned mammals involving the introduction of a diploid nucleus from a mature cell into an enucleated egg cell, illustrated by Dolly the sheep
Understand how cloned transgenic animals can be used to produce human proteins

Akọmọ Ojú-ẹkọ

Gardeners have been cloning plants for centuries - every time you take a cutting from a favourite rose bush and grow it into a new plant, you are producing a genetic clone. Modern tissue culture scales this up dramatically: from a few cells scraped off a parent plant, laboratories can generate thousands of identical plants in weeks. Animal cloning is harder, but Dolly the sheep showed it was possible, and the technique now has practical applications in medicine.

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Ayẹwo Ẹkọ

Ekele diri gi maka imecha ihe karịrị na Cloning. Ugbu a na ị na-enyochakwa isi echiche na echiche ndị dị mkpa, ọ bụ oge iji nwalee ihe ị ma. Ngwa a na-enye ụdị ajụjụ ọmụmụ dị iche iche emebere iji kwado nghọta gị wee nyere gị aka ịmata otú ị ghọtara ihe ndị a kụziri.

Ị ga-ahụ ngwakọta nke ụdị ajụjụ dị iche iche, gụnyere ajụjụ chọrọ ịhọrọ otu n’ime ọtụtụ azịza, ajụjụ chọrọ mkpirisi azịza, na ajụjụ ede ede. A na-arụpụta ajụjụ ọ bụla nke ọma iji nwalee akụkụ dị iche iche nke ihe ọmụma gị na nkà nke ịtụgharị uche.

Jiri akụkụ a nke nyocha ka ohere iji kụziere ihe ị matara banyere isiokwu ahụ ma chọpụta ebe ọ bụla ị nwere ike ịchọ ọmụmụ ihe ọzọ. Ekwela ka nsogbu ọ bụla ị na-eche ihu mee ka ị daa mba; kama, lee ha anya dị ka ohere maka ịzụlite onwe gị na imeziwanye.

What is an explant in micropropagation? A) A mature plant grown from seed B) A small piece of plant tissue taken from the parent C) A genetically modified seed D) A root cutting from an adult plant Answer: B
In the cloning of Dolly the sheep, where was the diploid nucleus taken from? A) An egg cell B) A sperm cell C) A body cell of an adult sheep D) An embryonic cell Answer: C
What triggers the enucleated egg cell to start dividing in adult cell cloning? A) Fertilisation by a sperm B) An electric shock C) Addition of hormones D) Exposure to UV light Answer: B
Which of the following is a disadvantage of cloning plants? A) The plants grow too quickly B) All plants are genetically identical so equally vulnerable to disease C) The plants cannot photosynthesise D) Cloned plants cannot reproduce Answer: B
What is pharming? A) Growing crops on fish farms B) Using cloned transgenic animals to produce human proteins in their milk C) Selective breeding of dairy cattle D) Fermenting milk to make yoghurt Answer: B