Biology - 4BI1 PearsonEdexcel

Genetic Modification (genetic Engineering)

Gbogbo ọrọ náà

What if you could take a single gene from one organism and place it inside another to give it entirely new capabilities? That is exactly what genetic modification makes possible. Scientists now routinely insert human genes into bacteria to manufacture life-saving medicines, and engineer crop plants to resist pests or survive drought.

This topic walks you through the tools of genetic engineering: restriction enzymes that cut DNA at precise locations, ligase that joins fragments together, plasmids and viruses that carry genes into new cells, and the fermenter technology that scales production to industrial levels. You will also explore the benefits and concerns surrounding genetically modified crops and the meaning of the term transgenic.

Ebumnobi

  1. Understand how restriction enzymes are used to cut DNA at specific sites and ligase enzymes are used to join pieces of DNA together
  2. Understand how plasmids and viruses can act as vectors, which take up pieces of DNA, and then insert this recombinant DNA into other cells
  3. Understand how large amounts of human insulin can be manufactured from genetically modified bacteria that are grown in a fermenter
  4. Understand how genetically modified plants can be used to improve food production
  5. Understand that the term transgenic means the transfer of genetic material from one species to a different species

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Akwụkwọ Ọmụmụ

In 1982, genetically engineered bacteria produced the first synthetic human insulin, replacing insulin extracted from pig and cow pancreases. Today, nearly all insulin used by diabetics worldwide comes from modified bacteria grown in industrial fermenters. The technique that made this possible - cutting a gene from one species and splicing it into another - is the foundation of modern genetic engineering.

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Nnyocha Ọmụmụ

Ekele diri gi maka imecha ihe karịrị na Genetic Modification (genetic Engineering). Ugbu a na ị na-enyochakwa isi echiche na echiche ndị dị mkpa, ọ bụ oge iji nwalee ihe ị ma. Ngwa a na-enye ụdị ajụjụ ọmụmụ dị iche iche emebere iji kwado nghọta gị wee nyere gị aka ịmata otú ị ghọtara ihe ndị a kụziri.

Ị ga-ahụ ngwakọta nke ụdị ajụjụ dị iche iche, gụnyere ajụjụ chọrọ ịhọrọ otu n’ime ọtụtụ azịza, ajụjụ chọrọ mkpirisi azịza, na ajụjụ ede ede. A na-arụpụta ajụjụ ọ bụla nke ọma iji nwalee akụkụ dị iche iche nke ihe ọmụma gị na nkà nke ịtụgharị uche.

Jiri akụkụ a nke nyocha ka ohere iji kụziere ihe ị matara banyere isiokwu ahụ ma chọpụta ebe ọ bụla ị nwere ike ịchọ ọmụmụ ihe ọzọ. Ekwela ka nsogbu ọ bụla ị na-eche ihu mee ka ị daa mba; kama, lee ha anya dị ka ohere maka ịzụlite onwe gị na imeziwanye.

  1. What is the function of restriction enzymes in genetic engineering? A) They join pieces of DNA together B) They cut DNA at specific base sequences C) They carry genes into host cells D) They copy DNA during cell division Answer: B
  2. Which structure acts as a vector in bacterial genetic engineering? A) Ribosome B) Chromosome C) Plasmid D) Mitochondrion Answer: C
  3. What enzyme joins the gene into the plasmid? A) Restriction enzyme B) DNA polymerase C) DNA ligase D) Amylase Answer: C
  4. Why are genetically modified bacteria grown in a fermenter? A) To prevent them from escaping B) To provide controlled conditions for rapid reproduction C) To expose them to sunlight D) To remove unwanted genes Answer: B
  5. What does the term transgenic mean? A) An organism with extra chromosomes B) An organism containing genes from a different species C) An organism that has been cloned D) An organism produced by selective breeding Answer: B

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